The medical world has built an infinite literature without any (except erroneous and vacillating) idea of cause. Medicine is rich in science, but now as well as in the past time, it suffers from a dearth of practical ideas. The average doctor is often educated out of all the common-sense he was born with.  He has facts-scientific facts galore--without ideas. Millions have facts, but no ideas. Thousands of doctors have all the scientific data needed, but they have not harnessed their science to common-sense and philosophy.

   Without a clear conception of cause, cure must remain the riddle that it is.  The late Sir James Mackenzie--while living, the greatest clinician in the world--declared: "In medical research the object is mainly the prevention and cure of disease."  If cause is not known, how is prevention or cure possible--as, for example, by producing a mild form of smallpox or other so-called disease by poisoning a healthy person by introducing into his body the pathological products of said disease? Certainly only pathological thinking can arrive at such conclusions. Vaccines and autogenous remedies are made from the products of disease, and the idea that disease can be made to cure itself is the end-product of pathological thinking. This statement is not so much incongruous after we consider the fact that all search and research work by medical scientists to find cause, has been made in dead and dying people. As ridiculous as it may appear, medical science has gone, and is still going, to the dead and dying to find cause.

    If prevention and cure mean producing disease, surely prevention and cure are not desirable. If prevention can be accomplished, then cures will not be needed.

     At the time of his death, Mackenzie was laboring to discover prevention. A more worthy work cannot be imagined. But the tragedy of his life was that he died from a preventable disease; and he could have cured this disease that killed him if his conception of cause had been in line with the Truth of Toxemia--the primary cause of all disease.

   In spite of Mackenzie's ambition to put the profession in possession of truth concerning prevention and cure, he died without a correct idea of even in what direction to look for this desirable knowledge, as evidenced by such statements as: "Our problems being the prevention of disease, we require a complete knowledge of disease in all its aspects before we can take steps to prevent its occurrence."  There is the crux of the whole subject.  It is not disease; it is cause; "in all its aspects" that we need to know before we can take steps to prevent "disease." Mackenzie stated the following concerning diagnosis:

        But it appears to be unlikely that in the present state of medicine there would be any great dissimilarity in the proportions of diagnosed and undiagnosed cases in many series of investigations such as we have made. The proportion depends, not on the skill or training of individual practitioners, but on the unsatisfactory state of all medical knowledge. The similarity of the statistical records from the institute and from private practice goes far to support this view.  In spite of the additional time given at the institute to the examination of cases which are undiagnosable in general practice, and the assistance given by the special departments-clinical groups--in their investigation, they remain profoundly obscure, although we know that it is from among them that there will gradually emerge the cases of advanced organic disease and the end-results which form so large a proportion of the inmates of hospital wards. And the tragedy is that many of them suffer from no serious disabilities, and might, but for our ignorance, be checked on their downward course.

Isn't that about as sharp a criticism of medical inefficiency as Tilden has ever made?

  This brings vividly to mind the statement, made only a short time ago, by Dr. Cabot, of Boston. that he himself was mistaken in his diagnoses about fifty per cent of the time--that he had proved it by post-mortems. Such a statement as this, coming from a man of his standing, means much. To it means that diagnoses is a meaningless term; for, as used, it means discovering what pathological effects--what changes--have been brought about by an undiscovered cause. Diagnoses means, in a few words, discovering effects which, when found, throw no light what ever on cause.

    Again I quote Mackenzie: "The knowledge of disease is so incomplete that we do not yet even know what steps should be taken to advance our knowledge." This being true, there is little excuse for laws to shut out or prevent cults from practicing less harmful palliations. How many reputable physicians have the honesty of Sir James Mackenzie?

  In spite of Mackenzie's high and worthy ambitions, he could not get away from the profession's stereotyped thinking. The early symptoms of disease he declared held the secret of their cause, and he believed an intense study of them would give the facts. But functional derangements are of the same nature and from the same universal cause that ends in all organic so-called diseases. All so-called diseases are, from beginning to end, the same evolutionary process.

   The study of pathology---the study of disease--has engaged the best minds in the profession always, and it surely appears that the last word must have been spoken on the subject; but the great Englishman believed, as all research workers believe, that a more intense and minute study of the early symptoms of disease will reveal the cause.  There is, however, one great reason why it cannot, and that is that all symptom-complexes--diseases---from their initiation to their ending, are effects, and the most intense study of any phase or stage of their progress will not throw any light on the cause.

   Cause is constant, ever present, and always the same. Only effects, and the object on which cause acts, change, and the change is most inconstant. To illustrate: A catarrh of the stomach presents first irritation, then inflammation, then ulceration, and finally induration and cancer. Not all causes run true to form; only a small percentage evolve to ulcer, and fewer still reach the cancer stage. More exit by way of acute food-poisoning or acute indigestion than by chronic diseases.

    In the early stages of this evolution there are all kinds of discomforts: more or less attacks of indigestion, frequent attacks of gastritis--sick stomach and vomiting. No two cases are alike. Nervous people suffer most, and some present all kinds of nervous symptoms--insomnia, headaches, etc. Woman have painful menstruation and hysterical symptoms--some are morose and others have epilepsy.  As the more chronic symptoms appear, those of the lymphatic temperament  do not suffer so much. As the disease progresses, a few  become pallid and develop pernicious anemia, due to gastric or intestinal ulceration and putrid protein infection; in others the first appearance of ulcer is manifested by a severe hemorrhage; others have a cachexia and a retention of food in the stomach, which is vomited every two or three days, caused by a partial closing of the pylorus.  These are usually malignant cases.

  To look upon any of these symptom-complexes as a distinct disease, requiring a distinct treatment, is to fall into the diagnostic maze that now bewilders the profession and renders treatment chaotic.

  It should be known to all discerning physicians that the earliest stage of organic disease is purely functional, evanescent, and never autogenerated so far as the affected organ is concerned, but is invariably due to an extraneous irritation (stimulation, if you please) augmented by Toxemia. When the irritation is not continuous, and toxin is eliminated as fast as developed, to the toleration point, normal functioning is resumed between the intervals of irritation and toxin excess.

  For example: a simple coryza (running at the nose--cold in the head), gastritis or colonitis.  At first these colds, catarrhs, or inflamations are periodic and functional; but, as the exciting cause or causes--local irritation and Toxemia---become more intense and continuous, the mucous membranes of these organs take on organic changes, which are given various names, such as irritation, inflammation, ulceration, and cancer. The pathology(organic change) may be studied until doomsday without throwing any light on the cause; for from the first irritation to the extreme ending--cachexia--which may be given the blanket term of tuberculosis, syphilis, or cancer, the whole pathologic panorama is one continuous evolution of intensifying effects.

    Germs and other so-called causes may be discovered in the course of pathological development, but they are accidental, coincidental, or at most auxiliary--or, to use the vernacular of law, obiter dicta.

  The proper way to study disease is to study health and every influence favorable or not to its continuance. Disease is perverted health. Any influence that lowers nerve-energy becomes disease-producing. Disease cannot be its own cause; neither can it be its own cure, and certainly not its own prevention.

  after years of wandering in the jungle of medical diagnosis--the usual guesswork of cause and effect, and the worse-than-guesswork of treatment, and becoming more confounded all the time--I resolved either to quit the profession or to find the cause of disease. To do this, it was necessary to exile myself from doctors and medical conventions; for I could not think for myself while listening to the babblings of babeldom. I took the advice found in Matt. 6:6. According to prevailing opinion, unless a doctor spends much time in medical societies and in the society of other doctors, takes postgraduate work, travels, etc., he cannot keep abreast of advancement.

     This opinion would be true if the sciences of medicine were fitted to a truthful etiology (efficient cause) of disease. But, since they are founded on no cause, or at most speculative and spectacular causes, as unstable as the sands of the sea, the doctor who cannot brook the bewilderment of vacillation is compelled to hide away from the voices of mistaken pedants and knowing blatherskites until stabilized. By that time ostracism will have overtaken him, and his fate, metaphorically speaking, will be that of the son of Zacharias.

  An honest search after truth too often, if not always, leads to the rack, stake, cross, or the blessed privilege of recanting; but the victim, by this time, decides as did the divine Jew: "Not My will, but Thine, be done;" or as Patrick Henry declared: "Give me liberty or give me death!"  The truth is larger than any man and until it is established, the memory of its advocate is not important. In the last analysis, is not the truth the only immortality? Man is an incident. If he discovers a truth, it benefits all who accept it. Truth too often must pray to be delivered fron its friends.

  I must acknowledge that I have not been very courteous to indifferent convention; and the truth I have discovered has suffered thereby. It has always appeared to me that the attention of fallacy-mongers cannot be attracted except by the use of a club or shillalah; and possibly my style of presenting my facts has caused too great a shock, and the desired effect has been lost in the reaction.

  That I have discovered the true cause of disease cannot be successfully disputed. This being true, my earnestness in presenting this great truth is justifiable.

  When I think back over my life, and remember the struggle I had with myself in supplanting my old beliefs with the new--the thousands of times I have suspected my own sanity--I then cannot be surprised at the opposition I have met and am meeting.(amen)

  My discovery of the truth that Toxemia is the cause of all so-called diseases came about slowly, step by step, with many dangerous skids.

  At first I believed that enervation must be the general cause of disease; then I decided that simple enervation is not disease, that disease must be due to poison, and that poison to be the general cause of disease, must be autogenerated; and if disease is due to autogenerated poison, what is the cause of that poison? I dallied long in endeavoring to trace disease back to poison taken into the system, such as food eaten after putrescence had begun, or from poisoning due to the development of putrescence after ingestion. In time I decided that poisoning per se is not disease. I observed where poisoning did not kill; some cases reacted and were soon in full health, while others remained in a state of semi-invalidism. I found the same thing true of injuries and mental shock. It took a long time to develop the thought that a poisoned or injured body, when not overwhelmed by Toxemia, would speedily return to the normal; and when it did not, there was a sick habit--a derangement of some kind--that a sick habit--a derangement of some kind--that required some such contingency to bring it within sense-perception.

  To illustrate : An injury to a joint is often complicated with rheumatism; the rheumatism previous to the injury was potentially in the blood.

  Just what change had taken place in the organism which, under stress of injury or shock of any kind, would cause a reaction with fever, I could not understand until the Toxemic Theory suggested itself to my mind, after which the cause of disease unfolded before me in an easy and natural manner. And now the theory is a proved fact.

  After years of perplexing thought and "watchful waiting," I learned that all disease, of whatever nature, was of slow development; that without systemic preparation even so-called acute systemic disease could not manifest.

  In a few words: Without Toxemia there can be no disease. I knew that the waste-product of metabolism was toxic, and that the only reason why we were not poisoned by it was because it was removed from the organism as fast as produced. Then I decided that the toxin was retained in the blood, when there was a checking of elimination. Then the cause of the checking had to be determined. In time I thought out the cause.  I knew that, when we had a normal nerve-energy, organic functioning was normal. Then came the thought that enervation caused a checking of elimination. Eureka! The cause of all so-called diseases is found! Enervation checks elimination of the waste-products of metabolism. Retention of metabolic toxin-----the first and only cause of disease!

Those that would be freed from the bondage of medical superstition should study "Toxemia Explained."  Next chapter # 3.